Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain

Abstract Background The role of the innate immune system in Alzheimer’s disease (AD) and neurodegenerative disease susceptibility has recently been highlighted in genetic studies. However, we do not know whether risk for inflammatory disease predisposes unaffected individuals to late-life cognitive...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Daniel Felsky, Ellis Patrick, Julie A. Schneider, Sara Mostafavi, Chris Gaiteri, Nikolaos Patsopoulos, David A. Bennett, Philip L. De Jager
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2018-07-01
Цуврал:	Molecular Neurodegeneration
Нөхцлүүд:	Genomics Alzheimer’s disease Microglia Inflammation Polygenic score Innate immunity
Онлайн хандалт:	http://link.springer.com/article/10.1186/s13024-018-0272-6
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!