Silencing of the von Willebrand factor gene in proatherothrombotic APOE∗3-Leiden.CETP transgenic mice

Background: Elevated von Willebrand factor (VWF) levels correlate with higher risk of atherosclerosis-related arterial thrombosis (atherothrombosis). Silencing the VWF gene via small-interfering RNAs (siRNAs) could mitigate this risk. Previous studies successfully delivered siRNA to the endothelium...

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Egile Nagusiak:	Yvonne K. Jongejan, Richard J. Dirven, Elisa Schrader Echeverri, Anke J.L. de Jong, Amanda C.M. Pronk, Sander Kooijman, Patrick C.N. Rensen, James E. Dahlman, Jeroen C.J. Eikenboom, Bart J.M. van Vlijmen
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2025-01-01
Saila:	Research and Practice in Thrombosis and Haemostasis
Gaiak:	atherothrombosis hypercholesterolemia mouse model siRNA von Willebrand factor
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2475037925000238
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