Targeting the NLRP3 inflammasome alleviates the comorbidity of chronic pain and depression via enhancing the autophagy
Abstract The comorbidity of chronic pain and depression exhibits the bidirectional relationship and forms a vicious cycle in disease development, diagnosis and therapy. NLRP3 inflammasome-mediated neuroinflammation is a crucial factor for the pathogenesis of pain and depression. The underlying mecha...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Portfolio
2026-01-01
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| Seri Bilgileri: | Scientific Reports |
| Konular: | |
| Online Erişim: | https://doi.org/10.1038/s41598-026-35400-0 |
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