The radioenhancer NBTXR3: bridging physics and biology to improve radiotherapy outcomes and prime anti-tumor immunity

Abstract Radiotherapy remains a cornerstone in cancer treatment, used in over 50% of cases. It employs ionizing radiation, primarily X-rays, to target and destroy tumors through direct DNA damage and indirect effects via reactive oxygen species. Despite technological advancements improving precision...

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Detalhes bibliográficos

Principais autores:	Célia Bienassis, Omar I. Vivar, Yun Hu, Jordan Da silva, Audrey Darmon, Julie Marill, Naeemunnisa Mohamed Anesary, Peter Schmitt, Laurent Levy, James Welsh, Yolanda Prezado, Frédérique Megnin-Chanet, Sébastien Paris
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	Journal of Experimental & Clinical Cancer Research
Assuntos:	Antitumor immunity Cancer Nanoparticle NBTXR3 Proton therapy Radioenhancer
Acesso em linha:	https://doi.org/10.1186/s13046-025-03579-1
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