Superior antitumor immune response achieved with proton over photon immunoradiotherapy is amplified by the nanoradioenhancer NBTXR3

Abstract Recent findings suggest that immunoradiotherapy (IRT), combining photon radiotherapy (XRT) or proton radiotherapy (PRT) with immune checkpoint blockade, can enhance systemic tumor control. However, the comparative efficacy of XRT and PRT in IRT remains understudied. To address this, we comp...

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Autores principales:	Yun Hu, Sébastien Paris, Narayan Sahoo, Qi Wang, Qianxia Wang, Hampartsoum B. Barsoumian, Ailing Huang, Jordan Da Silva, Célia Bienassis, Claudia S. Kettlun Leyton, Tiffany A. Voss, Fatemeh Masrorpour, Thomas Riad, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Jing Wang, Maria Angelica Cortez, James W. Welsh
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-10-01
Colección:	Journal of Nanobiotechnology
Materias:	NBTXR3 nanoradioenhancer Proton radiotherapy Photon radiotherapy Immunotherapy Lung cancer
Acceso en línea:	https://doi.org/10.1186/s12951-024-02855-0
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