Ethyl pyruvate protects against sepsis-associated encephalopathy through inhibiting the NLRP3 inflammasome

Abstract Background With the advance of antibiotics and life support therapy, the mortality of sepsis has been decreasing in recent years. However, the incidence of sepsis-associated encephalopathy (SAE), a common complication of sepsis, is still high. There are few effective therapies to treat clin...

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Autores principales:	Xiaoli Zhong, Lingli Xie, Xiaolong Yang, Fang Liang, Yanliang Yang, Jianbin Tong, Yanjun Zhong, Kai Zhao, Yiting Tang, Chuang Yuan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2020-06-01
Colección:	Molecular Medicine
Materias:	Sepsis-associated encephalopathy Ethyl pyruvate NLRP3 inflammasome Innate immunity Sepsis
Acceso en línea:	http://link.springer.com/article/10.1186/s10020-020-00181-3
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