Ethyl Pyruvate Attenuates Microglial NLRP3 Inflammasome Activation via Inhibition of HMGB1/NF-κB/miR-223 Signaling

Ethyl pyruvate is a molecule with anti-inflammatory and pro-metabolic effects. Ethyl pyruvate has been shown to ameliorate the clinical and pathological findings of neurodegenerative diseases such as Alzheimer’s and Parkinson’s Diseases in rodents. Its anti-inflammatory and neuroprotective effects a...

Полное описание

Библиографические подробности

Главные авторы:	Melis Olcum, Kemal Ugur Tufekci, Devrim Yagmur Durur, Bora Tastan, Irem Nur Gokbayrak, Kursad Genc, Sermin Genc
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2021-05-01
Серии:	Antioxidants
Предметы:	ethyl pyruvate microglia NLRP3 inflammasome microRNA HMGB1 NF-κB
Online-ссылка:	https://www.mdpi.com/2076-3921/10/5/745
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!