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mTORC2 Deficiency Alters the Metabolic Profile of Conventional Dendritic Cells

In myeloid dendritic cells (DC), deletion of the mechanistic target of rapamycin complex 2 (TORC2) results in an augmented pro-inflammatory phenotype and T cell stimulatory activity; however, the underlying mechanism has not been resolved. Here, we demonstrate that mouse bone marrow-derived TORC2-de...

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Xehetasun bibliografikoak
Egile Nagusiak: Alicia R. Watson, Helong Dai, Yawen Zheng, Ryosuke Nakano, Anastasios D. Giannou, Ashley V. Menk, Donna B. Stolz, Greg M. Delgoffe, Angus W. Thomson
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019-07-01
Saila:Frontiers in Immunology
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Sarrera elektronikoa:https://www.frontiersin.org/article/10.3389/fimmu.2019.01451/full
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