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Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma

Abstract Glioblastoma (GB) is the most frequent primary brain tumor in adults with a dismal prognosis despite aggressive treatment including surgical resection, radiotherapy and chemotherapy with the alkylating agent temozolomide. Thus far, the successful implementation of the concept of targeted th...

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Príomhchruthaitheoirí: Michael W. Ronellenfitsch, Pia S. Zeiner, Michel Mittelbronn, Hans Urban, Torsten Pietsch, Dirk Reuter, Christian Senft, Joachim P. Steinbach, Manfred Westphal, Patrick N. Harter
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2018-08-01
Sraith:Acta Neuropathologica Communications
Ábhair:
Rochtain ar líne:http://link.springer.com/article/10.1186/s40478-018-0583-4
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