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Model-Based Dose Escalation Designs in R with crmPack

Model-based dose escalation designs have gained increasing interest due to the need for more efficient and informative Phase I trials. The wide-spread implementation of such designs has been hindered by the need for either licensing specialized commercial software or programming the design and simul...

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Detalhes bibliográficos
Principais autores: Daniel Sabanés Bové, Wai Yin Yeung, Giuseppe Palermo, Thomas Jaki
Formato: Artigo
Idioma:Inglês
Publicado em: Foundation for Open Access Statistics 2019-06-01
Colecção:Journal of Statistical Software
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Acesso em linha:https://www.jstatsoft.org/index.php/jss/article/view/2762
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