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Pathogenesis of cerebral amyloid angiopathy caused by chaotic glymphatics—Mini-review

Cerebral amyloid angiopathy (CAA) is a common cause of lobar intracerebral hemorrhage in the elderly. It is also associated pathologically with Alzheimer’s disease (AD). Both CAA and AD share similar pathology of deposition amyloid beta fibrils (Aβ). Aβ is deposited mainly in the neurites in AD and...

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Principais autores: Forshing Lui, Jessa Alcaide, Stella Knowlton, Michael Ysit, Ning Zhong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-04-01
Serier:Frontiers in Neuroscience
Fag:
cerebral amyloid angiopathy
glymphatics
aquaporin-4
Aβ clearance
astrocytes
parenchymal border macrophages
Online adgang:https://www.frontiersin.org/articles/10.3389/fnins.2023.1180237/full
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