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Pathogenesis of cerebral amyloid angiopathy caused by chaotic glymphatics—Mini-review

Cerebral amyloid angiopathy (CAA) is a common cause of lobar intracerebral hemorrhage in the elderly. It is also associated pathologically with Alzheimer’s disease (AD). Both CAA and AD share similar pathology of deposition amyloid beta fibrils (Aβ). Aβ is deposited mainly in the neurites in AD and...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Forshing Lui, Jessa Alcaide, Stella Knowlton, Michael Ysit, Ning Zhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2023-04-01
Schriftenreihe:Frontiers in Neuroscience
Schlagworte:
cerebral amyloid angiopathy
glymphatics
aquaporin-4
Aβ clearance
astrocytes
parenchymal border macrophages
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fnins.2023.1180237/full
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