Improved next-generation sequencing pre-capture library yields and sequencing parameters using on-bead PCR

Tumor DNA sequencing results can have important clinical implications. However, its use is often limited by low DNA input, owing to small tumor biopsy size. To help overcome this limitation we have developed a simple improvement to a commonly used next-generation sequencing (NGS) capture-based libra...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Christopher R McEvoy, Timothy Semple, Bhargavi Yellapu, David Y Choong, Huiling Xu, Gisela Mir Arnau, Andrew P Fellowes, Stephen B Fox
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Taylor & Francis Group 2020-01-01
Цуврал:	BioTechniques
Нөхцлүүд:	DNA library next-generation sequencing solid-phase reversible immobilization beads
Онлайн хандалт:	https://www.future-science.com/doi/10.2144/btn-2019-0059
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!