Multiplex PCR-based next generation sequencing as a novel, targeted and accurate molecular approach for periprosthetic joint infection diagnosis

ObjectivesPeriprosthetic joint infection (PJI) diagnosis remains challenging, and the identification of the causative microorganism is, by far, the most important aspect. Here, we use multiple PCR-based targeted next-generation sequencing (tNGS) to detect pathogens in PJI. To explore 1. the ability...

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Detalhes bibliográficos

Principais autores:	Changyu Huang, Ying Huang, Ziwen Wang, Yiming Lin, Yongbin Li, Yang Chen, Xiaoqing Chen, Chaofan Zhang, Wenbo Li, Wenming Zhang, Xinyu Fang, Zida Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-05-01
coleção:	Frontiers in Microbiology
Assuntos:	periprosthetic joint infection targeted next-generation sequencing metagenomic next-generation sequencing culture diagnostics
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1181348/full
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