The CagRS Two-Component System Regulates Clavulanic Acid Metabolism via Multiple Pathways in Streptomyces clavuligerus F613-1

Streptomyces clavuligerus F613-1 produces a clinically important β-lactamase inhibitor, clavulanic acid (CA). Although the biosynthesis pathway of CA has essentially been elucidated, the global regulatory mechanisms of CA biosynthesis remain unclear. The paired genes cagS and cagR, which are annotat...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Jiafang Fu, Ronghuo Qin, Gongli Zong, Cheng Liu, Ni Kang, Chuanqing Zhong, Guangxiang Cao
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Frontiers Media S.A. 2019-02-01
श्रृंखला:	Frontiers in Microbiology
विषय:	Streptomyces clavuligerus clavulanic acid CagRS arginine glyceraldehyde 3-phosphate primary metabolism
ऑनलाइन पहुंच:	https://www.frontiersin.org/article/10.3389/fmicb.2019.00244/full
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