Regulatory landscape fusion in rhabdomyosarcoma through interactions between the PAX3 promoter and FOXO1 regulatory elements

Abstract Background The organisation of vertebrate genomes into topologically associating domains (TADs) is believed to facilitate the regulation of the genes located within them. A remaining question is whether TAD organisation is achieved through the interactions of the regulatory elements within...

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Principais autores:	Cristina Vicente-García, Barbara Villarejo-Balcells, Ibai Irastorza-Azcárate, Silvia Naranjo, Rafael D. Acemel, Juan J. Tena, Peter W. J. Rigby, Damien P. Devos, Jose L. Gómez-Skarmeta, Jaime J. Carvajal
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2017-06-01
Serija:	Genome Biology
Teme:	TAD CTCF Transcriptional regulation FOXO1 PAX3 Alveolar rhabdomyosarcoma
Online dostop:	http://link.springer.com/article/10.1186/s13059-017-1225-z
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