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STING-ERO1 signaling exacerbates PARylation-mediated parthanatos in sepsis

Abstract Background Sepsis is a life-threatening condition characterized by uncontrolled inflammation, oxidative stress, and aberrant cell death. Although the STING pathway is well established as a central mediator of innate immunity, its functions beyond interferon signaling remain largely undefine...

Deskribapen osoa

Gorde:
Egile Nagusiak: Xuanheng Li, Qianzheng Zhou, Xufei Zhang, Yangguang Li, Yiyu Yang, Jie Wu, Qinjie Liu, Peizhao Liu, Haiyang Jiang, Juanhan Liu, Liting Deng, Zexing Lin, Cunxia Wu, Lei Wu, Yun Zhao, Jianan Ren, Xiuwen Wu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2026-03-01
Saila:Cell Communication and Signaling
Gaiak:
PARP1
Poly ADP-ribosylation
ERO1
STING
Parthanatos
Sarrera elektronikoa:https://doi.org/10.1186/s12964-026-02791-6
Etiketak: Etiketa erantsi
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