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STING-ERO1 signaling exacerbates PARylation-mediated parthanatos in sepsis

Abstract Background Sepsis is a life-threatening condition characterized by uncontrolled inflammation, oxidative stress, and aberrant cell death. Although the STING pathway is well established as a central mediator of innate immunity, its functions beyond interferon signaling remain largely undefine...

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Príomhchruthaitheoirí: Xuanheng Li, Qianzheng Zhou, Xufei Zhang, Yangguang Li, Yiyu Yang, Jie Wu, Qinjie Liu, Peizhao Liu, Haiyang Jiang, Juanhan Liu, Liting Deng, Zexing Lin, Cunxia Wu, Lei Wu, Yun Zhao, Jianan Ren, Xiuwen Wu
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2026-03-01
Sraith:Cell Communication and Signaling
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s12964-026-02791-6
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