The Making and Breaking of Serine-ADP-Ribosylation in the DNA Damage Response
ADP-ribosylation is a widespread posttranslational modification that is of particular therapeutic relevance due to its involvement in DNA repair. In response to DNA damage, PARP1 and 2 are the main enzymes that catalyze ADP-ribosylation at damage sites. Recently, serine was identified as the primary...
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| Principais autores: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2021-11-01
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| Serija: | Frontiers in Cell and Developmental Biology |
| Teme: | |
| Online dostop: | https://www.frontiersin.org/articles/10.3389/fcell.2021.745922/full |
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