Plasma and CSF Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: A Cross-Sectional and Longitudinal Study

Background: Neurofilament light chain (NfL) is a validated biofluid marker of neuroaxonal damage with great potential for monitoring patients with neurodegenerative diseases. We aimed to further validate the clinical utility of plasma (p) vs. CSF (c) NfL for distinguishing patients with Amyotrophic...

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Hlavní autoři:	Veria Vacchiano, Andrea Mastrangelo, Corrado Zenesini, Marco Masullo, Corinne Quadalti, Patrizia Avoni, Barbara Polischi, Arianna Cherici, Sabina Capellari, Fabrizio Salvi, Rocco Liguori, Piero Parchi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-10-01
Edice:	Frontiers in Aging Neuroscience
Témata:	neurofilament light chain amyotrophic lateral sclerosis diagnosis prognosis longitudinal Simoa
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fnagi.2021.753242/full
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