Plasma and CSF Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: A Cross-Sectional and Longitudinal Study

Background: Neurofilament light chain (NfL) is a validated biofluid marker of neuroaxonal damage with great potential for monitoring patients with neurodegenerative diseases. We aimed to further validate the clinical utility of plasma (p) vs. CSF (c) NfL for distinguishing patients with Amyotrophic...

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Autori principali:	Veria Vacchiano, Andrea Mastrangelo, Corrado Zenesini, Marco Masullo, Corinne Quadalti, Patrizia Avoni, Barbara Polischi, Arianna Cherici, Sabina Capellari, Fabrizio Salvi, Rocco Liguori, Piero Parchi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-10-01
Serie:	Frontiers in Aging Neuroscience
Soggetti:	neurofilament light chain amyotrophic lateral sclerosis diagnosis prognosis longitudinal Simoa
Accesso online:	https://www.frontiersin.org/articles/10.3389/fnagi.2021.753242/full
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