Plasma and CSF Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: A Cross-Sectional and Longitudinal Study

Background: Neurofilament light chain (NfL) is a validated biofluid marker of neuroaxonal damage with great potential for monitoring patients with neurodegenerative diseases. We aimed to further validate the clinical utility of plasma (p) vs. CSF (c) NfL for distinguishing patients with Amyotrophic...

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Bibliografische Detailangaben

Hauptverfasser:	Veria Vacchiano, Andrea Mastrangelo, Corrado Zenesini, Marco Masullo, Corinne Quadalti, Patrizia Avoni, Barbara Polischi, Arianna Cherici, Sabina Capellari, Fabrizio Salvi, Rocco Liguori, Piero Parchi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-10-01
Schriftenreihe:	Frontiers in Aging Neuroscience
Schlagworte:	neurofilament light chain amyotrophic lateral sclerosis diagnosis prognosis longitudinal Simoa
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fnagi.2021.753242/full
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