Neuronal Extracellular Vesicles Carrying APOE Downregulate Filament Actin Polymerization Signaling to Inhibit Synapse Formation in Alzheimer's Disease

ABSTRACT Synaptic formation impairment is closely correlated with cognitive impairment in Alzheimer's disease (AD), yet the underlying mechanisms remain incompletely understood. Emerging evidence indicates that extracellular vesicles (EVs), critical mediators of intercellular communication, are impl...

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Váldodahkkit:	Yang Yu, Zhixin Ma, Taixu Li, Wenjun Xiao, Zhigang Li
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Wiley 2026-03-01
Ráidu:	Journal of Extracellular Vesicles
Fáttát:	Alzheimer's disease APOE extracellular vesicles synapse
Liŋkkat:	https://doi.org/10.1002/jev2.70248
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