Neuronal Extracellular Vesicles Carrying APOE Downregulate Filament Actin Polymerization Signaling to Inhibit Synapse Formation in Alzheimer's Disease

ABSTRACT Synaptic formation impairment is closely correlated with cognitive impairment in Alzheimer's disease (AD), yet the underlying mechanisms remain incompletely understood. Emerging evidence indicates that extracellular vesicles (EVs), critical mediators of intercellular communication, are impl...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Yang Yu, Zhixin Ma, Taixu Li, Wenjun Xiao, Zhigang Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2026-03-01
Serie:	Journal of Extracellular Vesicles
Soggetti:	Alzheimer's disease APOE extracellular vesicles synapse
Accesso online:	https://doi.org/10.1002/jev2.70248
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!