Neuronal Extracellular Vesicles Carrying APOE Downregulate Filament Actin Polymerization Signaling to Inhibit Synapse Formation in Alzheimer's Disease

ABSTRACT Synaptic formation impairment is closely correlated with cognitive impairment in Alzheimer's disease (AD), yet the underlying mechanisms remain incompletely understood. Emerging evidence indicates that extracellular vesicles (EVs), critical mediators of intercellular communication, are impl...

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Үндсэн зохиолчид:	Yang Yu, Zhixin Ma, Taixu Li, Wenjun Xiao, Zhigang Li
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2026-03-01
Цуврал:	Journal of Extracellular Vesicles
Нөхцлүүд:	Alzheimer's disease APOE extracellular vesicles synapse
Онлайн хандалт:	https://doi.org/10.1002/jev2.70248
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!