SARM1 participates in axonal degeneration and mitochondrial dysfunction in prion disease

Prion disease represents a group of fatal neurogenerative diseases in humans and animals that are associated with energy loss, axonal degeneration, and mitochondrial dysfunction. Axonal degeneration is an early hallmark of neurodegeneration and is triggered by SARM1. We found that depletion or dysfu...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Meng-Yu Lai, Jie Li, Xi-Xi Zhang, Wei Wu, Zhi-Ping Li, Zhi-Xin Sun, Meng-Yang Zhao, Dong-Ming Yang, Dong-Dong Wang, Wen Li, De-Ming Zhao, Xiang-Mei Zhou, Li-Feng Yang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wolters Kluwer Medknow Publications 2022-01-01
Serie:	Neural Regeneration Research
Soggetti:	axonal degeneration; mitochondrial dysfunction; nad+ metabolism; nadase; neurodegenerative disease; prion disease; sarm1; sterile alpha and tir motif-containing 1
Accesso online:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=10;spage=2293;epage=2299;aulast=Lai
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!