Unveiling the Relationship between Ceftobiprole and High-Molecular-Mass (HMM) Penicillin-Binding Proteins (PBPs) in <i>Enterococcus faecalis</i>
Low-affinity PBP4, historically linked to penicillin resistance in <i>Enterococcus faecalis</i>, may still have affinity for novel cephalosporins. Ceftobiprole (BPR) is a common therapeutic choice, even with PBP4-related overexpression and amino acid substitution due to mutations. Our study aims to...
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| Автори: | , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2024-01-01
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| Серія: | Antibiotics |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/2079-6382/13/1/65 |
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