Strain-dependent modifiers exacerbate familial leukemia caused by GATA1-deficiency
Abstract GATA1 plays a critical role in differentiation, proliferation, and apoptosis during erythropoiesis. We developed a Gata1 knock-down allele (Gata1.05) that results in GATA1 expression at 5% of endogenous level. In female mice heterozygous for both the Gata1.05 and wild-type alleles, we obser...
שמור ב:
| Principais autores: | , , , , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BMC
2024-02-01
|
| סדרה: | Experimental Hematology & Oncology |
| נושאים: | |
| גישה מקוונת: | https://doi.org/10.1186/s40164-024-00491-w |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|
