Strain-dependent modifiers exacerbate familial leukemia caused by GATA1-deficiency
Abstract GATA1 plays a critical role in differentiation, proliferation, and apoptosis during erythropoiesis. We developed a Gata1 knock-down allele (Gata1.05) that results in GATA1 expression at 5% of endogenous level. In female mice heterozygous for both the Gata1.05 and wild-type alleles, we obser...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2024-02-01
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| Serie: | Experimental Hematology & Oncology |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s40164-024-00491-w |
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