Targeted genome engineering in human induced pluripotent stem cells by penetrating TALENs
Background: Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) have been successfully used to knock out endogenous genes in stem cell research. However, the deficiencies of current gene-based delivery systems may hamper the clinical application of these nucleas...
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| Автори: | , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
SpringerOpen
2013-01-01
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| Серія: | Cell Regeneration |
| Предмети: | |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S204597691730041X |
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