Targeted genome engineering in human induced pluripotent stem cells by penetrating TALENs

Background: Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) have been successfully used to knock out endogenous genes in stem cell research. However, the deficiencies of current gene-based delivery systems may hamper the clinical application of these nucleas...

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Hlavní autoři:	Renli Ru, Yongchao Yao, Songlin Yu, Benpeng Yin, Wanwan Xu, Siting Zhao, Li Qin, Xiaoping Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	SpringerOpen 2013-01-01
Edice:	Cell Regeneration
Témata:	CCR5 HIV-1 Cell-penetrating peptide TALEN TAT Protein delivery Induced pluripotent stem cells
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S204597691730041X
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