Transcending the challenge of evolving resistance mechanisms in Pseudomonas aeruginosa through β-lactam-enhancer-mechanism-based cefepime/zidebactam

ABSTRACTMulti-drug resistant (MDR) Pseudomonas aeruginosa harbor a complex array of β-lactamases and non-enzymatic resistance mechanisms. In this study, the activity of a β-lactam/β-lactam-enhancer, cefepime/zidebactam, and novel β-lactam/β-lactamase inhibitor combinations was determined against an...

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Bibliografske podrobnosti

Principais autores:	Andrea M. Hujer, Steven H. Marshall, Andrew R. Mack, Kristine M. Hujer, Yamuna Devi Bakthavatchalam, Kushal Umarkar, Snehal R. Palwe, Swapna Takalkar, Prashant R. Joshi, Rahul Shrivastava, Hariharan Periasamy, Sachin S. Bhagwat, Mahesh V. Patel, Balaji Veeraraghavan, Robert A. Bonomo
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology 2023-12-01
Serija:	mBio
Teme:	ß-lactamases antibiotic resistance Pseudomonas aeruginosa cefepime zidebactam ß-lactam enhancer
Online dostop:	https://journals.asm.org/doi/10.1128/mbio.01118-23
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