4′-C-Aminoethoxy modification enhanced nuclease resistance of RNAs and improved thermal stability of RNA duplexes
We designed and synthesized RNAs containing 4′-C-aminoethoxy-2′-O-methyluridine (4′-AEoU), and compared their properties with those containing 4′-C-aminopropyl-2′-O-methyluridine (4′-APU). The RNA duplexes containing 4′-AEoU showed higher melting temperatures than those containing 4′-APU. The 4′-AEo...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2021-01-01
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| Edice: | Results in Chemistry |
| Témata: | |
| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S2211715621001363 |
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