The Glycolysis-HIF-1α axis induces IL-1β of macrophages in rheumatoid arthritis

Abstract Background Rheumatoid arthritis (RA) is an aggressive, systemic autoimmune disease in which overactivated macrophages play a critical role in its pathogenesis. This study aimed to explore the potential role of glycolytic reprogramming in the production of proinflammatory cytokines by macrop...

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Autors principals:	Yimeng Jia, Rongli Li, Linfang Huang, Xunyao Wu, Lidan Zhao, Huaxia Yang, Xin You, Yunyun Fei
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-09-01
Col·lecció:	Arthritis Research & Therapy
Matèries:	Rheumatoid arthritis Macrophage Glycolysis HIF-1α IL-1β
Accés en línia:	https://doi.org/10.1186/s13075-025-03647-z
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