HIF-1α Stabilization in Flagellin-Stimulated Human Bronchial Cells Impairs Barrier Function

The respiratory epithelium provides a first line of defense against pathogens. Hypoxia-inducible factor (HIF)1α is a transcription factor which is stabilized in hypoxic conditions through the inhibition of prolyl-hydroxylase (PHD)2, the enzyme that marks HIF1α for degradation. Here, we studied the i...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Ivan Ramirez-Moral, Bianca L. Ferreira, Joe M. Butler, Michel van Weeghel, Natasja A. Otto, Alex F. de Vos, Xiao Yu, Menno D. de Jong, Riekelt H. Houtkooper, Tom van der Poll
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2022-01-01
Sarja:	Cells
Aiheet:	immunometabolism HIF1α airway epithelial cells flagellin inflammation
Linkit:	https://www.mdpi.com/2073-4409/11/3/391
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!