Dual risk of anticholinergic burden and CSF alzheimer’s biomarkers in older patients: a mortality follow-up study from daily medical practice

Abstract Background Anticholinergic medications are widely prescribed to older adults and are linked to increased mortality and cognitive decline. Cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease (AD)—amyloid and tau—are strong prognostic indicators in neurocognitive disorders (NCD). Howe...

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Hauptverfasser: Théodore Decaix, Julien Dumurgier, Emmanuel Cognat, Karl Götze, François Mouton-Liger, Jacques Hugon, Elodie Bouaziz-Amar, Matthieu Lilamand, Claire Paquet
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-07-01
Schriftenreihe:Alzheimer’s Research & Therapy
Schlagworte:
Anticholinergic medication
Cognition
Dementia
Older adult
Clinical practice
Online Zugang:https://doi.org/10.1186/s13195-025-01814-7
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