Formulation and optimization of polymeric agglomerates of Bosentan monohydrate by crystallo-co-agglomeration technique

Abstract Background The polymeric spherical agglomerate of Bosentan monohydrate was prepared by crystallo-co-agglomeration technique, for enhancing the micrometric properties and solubility of the drug. The agglomerates were developed using two distinct solvents, DCM as a good solvent and bridging l...

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Үндсэн зохиолчид:	Umang Varia, Azad Patel, Hitesh Katariya, Krunal Detholia
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	SpringerOpen 2022-05-01
Цуврал:	Bulletin of the National Research Centre
Нөхцлүүд:	Crystallo-co-agglomeration technique Spherical agglomerates Box–Behnken design In vitro drug release Gas chromatography
Онлайн хандалт:	https://doi.org/10.1186/s42269-022-00837-6
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!