Formulation and optimization of polymeric agglomerates of Bosentan monohydrate by crystallo-co-agglomeration technique
Abstract Background The polymeric spherical agglomerate of Bosentan monohydrate was prepared by crystallo-co-agglomeration technique, for enhancing the micrometric properties and solubility of the drug. The agglomerates were developed using two distinct solvents, DCM as a good solvent and bridging l...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SpringerOpen
2022-05-01
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| Serie: | Bulletin of the National Research Centre |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s42269-022-00837-6 |
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