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Potential capacity of aptamers to trigger immune activation in human blood.

Target specific short single-stranded DNA (ssDNA) molecules, called aptamers, are auspicious ligands for numerous in vivo applications. However, aptamers are synthetic molecules, which might be recognized by the immune cells in vivo and induce an activation of the innate immune system. Thus, immune...

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Autors principals: Meltem Avci-Adali, Heidrun Steinle, Tatjana Michel, Christian Schlensak, Hans P Wendel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3720859?pdf=render
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