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Generation of iPSCs by Nonintegrative RNA-Based Reprogramming Techniques: Benefits of Self-Replicating RNA versus Synthetic mRNA

The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is gaining in importance in the fields of regenerative medicine, tissue engineering, and disease modeling. Patient-specific iPSCs have as an unlimited cell source a tremendous potential for generating various types of aut...

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Библиографические подробности
Главные авторы: Heidrun Steinle, Marbod Weber, Andreas Behring, Ulrike Mau-Holzmann, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley 2019-01-01
Серии:Stem Cells International
Online-ссылка:http://dx.doi.org/10.1155/2019/7641767
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