QR Code

Structure and mechanism of the RalGAP tumor suppressor complex

Abstract The RalGAP (GTPase activating protein) complexes are negative regulators of the Ral GTPases and thus crucial components that counteract oncogenic Ras signaling. However, no structural information on the architecture of this tumor suppressor complex is available hampering a mechanistic under...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: René Rasche, Björn Udo Klink, Lisa Helene Apken, Esther Michalke, Minghao Chen, Andrea Oeckinghaus, Christos Gatsogiannis, Daniel Kümmel
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2025-07-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-025-61743-9
Ngā Tūtohu: Tāpirihia he Tūtohu
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!