The RalGAPα1–RalA signal module protects cardiac function through regulating calcium homeostasis
Here the authors show that a RalGAPα1-RalA signal nexus regulates calcium homeostasis in cardiomyocytes via the calcium pump SERCA2a, which plays a protective role to maintain cardiac function under pressure overload conditions.
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| Principais autores: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2022-07-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-022-31992-z |
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