RalGAP complexes control secretion and primary cilia in pancreatic disease

Loss of RalGAP impacts secretion, cell polarity, and primary cilium formation, results in pancreatitis and neoplasia development in the pancreas, and promotes mutant KRas-driven tumorigenesis. κB-Ras/RalGAP complexes limit the activity of Ral GTPases, which function in EGFR/Ras signaling. RalGAP exp...

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Үндсэн зохиолчид:	Lisa H Apken, Hannah Barz, Stephanie Beel, Esther Michalke, René Rasche, Archana Verma, Andrea Ricker, Harald Nüsse, Jürgen Klingauf, Kornelius Kerl, Eva Wardelmann, Daniel Kümmel, Konrad Steinestel, Zoltán Pethő, Michael Meisterernst, Andrea Oeckinghaus
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Life Science Alliance LLC 2025-08-01
Цуврал:	Life Science Alliance
Онлайн хандалт:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202403123
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!