Brain-derived and in vitro-seeded alpha-synuclein fibrils exhibit distinct biophysical profiles
The alpha-synuclein (αSyn) seeding amplification assay (SAA) that allows the generation of disease-specific in vitro seeded fibrils (SAA fibrils) is used as a research tool to study the connection between the structure of αSyn fibrils, cellular seeding/spreading, and the clinicopathological manifestatio...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications Ltd
2024-11-01
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| Serie: | eLife |
| Soggetti: | |
| Accesso online: | https://elifesciences.org/articles/92775 |
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