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Nrf2-dependent effects of CDDO-Me on bactericidal activity in macrophage infection models

IntroductionDiabetes and chronic kidney disease (CKD) increase susceptibility to bacterial infections, particularly Staphylococcus aureus, which is associated with highmortality in CKD patients. Dysregulated macrophage activity and excessive oxidative stress exacerbate immune dysfunction and inflamm...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Therese B. Deramaudt, Ahmad Chehaitly, Marcel Bonay
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2025-05-01
Sraith:Frontiers in Immunology
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574776/full
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