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Nrf2-dependent effects of CDDO-Me on bactericidal activity in macrophage infection models

IntroductionDiabetes and chronic kidney disease (CKD) increase susceptibility to bacterial infections, particularly Staphylococcus aureus, which is associated with highmortality in CKD patients. Dysregulated macrophage activity and excessive oxidative stress exacerbate immune dysfunction and inflamm...

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Principais autores: Therese B. Deramaudt, Ahmad Chehaitly, Marcel Bonay
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2025-05-01
Serija:Frontiers in Immunology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574776/full
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