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Estimation of pyrazinamidase activity using a cell-free In vitro synthesis of pnca and its association with pyrazinamide susceptibility in Mycobacterium tuberculosis

Background: The main mechanism of resistance to PZA in Mycobacterium tuberculosis relies on mutations on its pyrazinamidase/nicotinamidase. Recently, a rapid colorimetric test relying on the PCR-based in vitro-synthesized-PZase assay has been reported for PZase activity determination from clinical M...

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Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Daniel Rueda, Christine Bernard, Lucas Gandy, Estelle Capton, Rachid Boudjelloul, Florence Brossier, Nicolas Veziris, Mirko Zimic, Wladimir Sougakoff
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Wolters Kluwer Medknow Publications 2018-01-01
Sraith:International Journal of Mycobacteriology
Ábhair:
Rochtain ar líne:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2018;volume=7;issue=1;spage=16;epage=25;aulast=Rueda
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