Estimation of pyrazinamidase activity using a cell-free In vitro synthesis of pnca and its association with pyrazinamide susceptibility in Mycobacterium tuberculosis

Background: The main mechanism of resistance to PZA in Mycobacterium tuberculosis relies on mutations on its pyrazinamidase/nicotinamidase. Recently, a rapid colorimetric test relying on the PCR-based in vitro-synthesized-PZase assay has been reported for PZase activity determination from clinical M...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Daniel Rueda, Christine Bernard, Lucas Gandy, Estelle Capton, Rachid Boudjelloul, Florence Brossier, Nicolas Veziris, Mirko Zimic, Wladimir Sougakoff
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Wolters Kluwer Medknow Publications 2018-01-01
سلاسل:	International Journal of Mycobacteriology
الموضوعات:	Cell-free expression Mycobacterium tuberculosis PncA pyrazinamidase pyrazinamide resistance tuberculosis
الوصول للمادة أونلاين:	http://www.ijmyco.org/article.asp?issn=2212-5531;year=2018;volume=7;issue=1;spage=16;epage=25;aulast=Rueda
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!