Dissecting tumor microenvironment heterogeneity in syngeneic mouse models: insights on cancer-associated fibroblast phenotypes shaped by infiltrating T cells

Murine syngeneic tumor models have been used extensively for cancer research for several decades and have been instrumental in driving the discovery and development of cancer immunotherapies. These tumor models are very simplistic cancer models, but recent reports have, however, indicated that the d...

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Detalhes bibliográficos

Principais autores:	Marco Carretta, Marie-Louise Thorseth, Aimilia Schina, Dennis Alexander Agardy, Astrid Zedlitz Johansen, Kevin James Baker, Shawez Khan, Anne Mette Askehøj Rømer, Klaire Yixin Fjæstad, Hannes Linder, Dorota Ewa Kuczek, Marco Donia, Lars Grøntved, Daniel Hargbøl Madsen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-01-01
coleção:	Frontiers in Immunology
Assuntos:	tumor microenvironment cancer-associated fibroblasts syngeneic mouse cancer models immunotherapy immunosuppressive mechanisms stroma
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1320614/full
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