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The Novel Alpha-2 Adrenoceptor Inhibitor Beditin Reduces Cytotoxicity and Huntingtin Aggregates in Cell Models of Huntington’s Disease

Huntington’s disease (HD) is a monogenetic neurodegenerative disorder characterized by the accumulation of polyglutamine-expanded huntingtin (mHTT). There is currently no cure, and therefore disease-slowing remedies are sought to alleviate symptoms of the multifaceted disorder. Encouraging findings...

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Bibliografski detalji
Glavni autori: Elisabeth Singer, Lilit Hunanyan, Magda M. Melkonyan, Jonasz J. Weber, Lusine Danielyan, Huu Phuc Nguyen
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2021-03-01
Serija:Pharmaceuticals
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Online pristup:https://www.mdpi.com/1424-8247/14/3/257
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